FluoroFinder

	Supplier	LifeSpan
	Catalog #:	LS-C701967-200 (View supplier product page)
	Size	200 μl
	Price
	Antigen	CXCL11
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	Cy3
	Target Species	Human
	Applications	WB
	Description	CXCL11 Antibody (aa22-94, Cy3)

	CXCL11	Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This antimicrobial gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014]
	Cy3	Cy3 is an important historical fluorophore from GE Healthcare. It has an excitation peak at 554 nm and an emission peak at 568 nm. Spectrally its similar to Alexa Fluor™ 555.

	Additional Sources

CXCL11 / Cy3 /