NR1H3 / Cy3 /
NR1H3 / Cy3 /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C701914-100 (View supplier product page) | |
| Size | 100 μl | |
| Price | ||
| Antigen | NR1H3 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Cy3 | |
| Target Species | Human, Mouse | |
| Applications | WB | |
| Description | NR1H3 / LXR Alpha Antibody (aa93-432, Cy3) |
About NR1H3 and Cy3
| NR1H3 | The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] | |
|---|---|---|
| Cy3 | Cy3 is an important historical fluorophore from GE Healthcare. It has an excitation peak at 554 nm and an emission peak at 568 nm. Spectrally its similar to Alexa Fluor™ 555. |
Citations
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