Arrestin beta 2 / Cy3 /
Arrestin beta 2 / Cy3 /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C701787-100 (View supplier product page) | |
| Size | 100 μl | |
| Price | ||
| Antigen | Arrestin beta 2 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Cy3 | |
| Target Species | Human | |
| Applications | WB | |
| Description | ARRB2 / Beta Arrestin 2 Antibody (aa262-430, Cy3) |
About Arrestin beta 2 and Cy3
| Arrestin beta 2 | Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012] | |
|---|---|---|
| Cy3 | Cy3 is an important historical fluorophore from GE Healthcare. It has an excitation peak at 554 nm and an emission peak at 568 nm. Spectrally its similar to Alexa Fluor™ 555. |
Citations
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