ABCG2 / DyLight 755 / MM0047-2J39

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB110-93511IR (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen ABCG2
Clone MM0047-2J39
Host Mouse
Isotype IgG2
Conjugate DyLight 755
Target Species Human
Applications FC, IHC-P, IHC
Description This was selected for its ability to detect human ABCG2 by flow cytometry and immunocytochemistry.
About ABCG2 and DyLight 755
ABCG2 The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra