FluoroFinder

	Supplier	LifeSpan
	Catalog #:	LS-C701358-200 (View supplier product page)
	Size	200 μl
	Price
	Antigen	mTOR
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	Cy3
	Target Species	Human
	Applications	WB
	Description	MTOR Antibody (aa2226-2488, Cy3)

	mTOR	The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This kinase is a component of two distinct complexes, mTORC1, which controls protein synthesis, cell growth and proliferation, and mTORC2, which is a regulator of the actin cytoskeleton, and promotes cell survival and cell cycle progression. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. Inhibitors of mTOR are used in organ transplants as immunosuppressants, and are being evaluated for their therapeutic potential in SARS-CoV-2 infections. Mutations in this gene are associated with Smith-Kingsmore syndrome and somatic focal cortical dysplasia type II. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Aug 2020]
	Cy3	Cy3 is an important historical fluorophore from GE Healthcare. It has an excitation peak at 554 nm and an emission peak at 568 nm. Spectrally its similar to Alexa Fluor™ 555.

	Additional Sources

mTOR / Cy3 /