FluoroFinder

	Supplier	LifeSpan
	Catalog #:	LS-C699768-200 (View supplier product page)
	Size	200 μl
	Price
	Antigen	CD162
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	Cy3
	Target Species	Mouse
	Applications	WB
	Description	SELPLG / PSGL-1 / CD162 Antibody (aa94-345, Cy3)

	CD162	This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]
	Cy3	Cy3 is an important historical fluorophore from GE Healthcare. It has an excitation peak at 554 nm and an emission peak at 568 nm. Spectrally its similar to Alexa Fluor™ 555.

	Additional Sources

CD162 / Cy3 /