ER-HR3 / DyLight 680 / ER-HR3

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-64931FR (View supplier product page)
Size 0.125 ml
Price $464.00
Antigen ER-HR3
Clone ER-HR3
Host Rat
Isotype IgG2c
Conjugate DyLight 680
Target Species Mouse
Applications FC, IHC-Fr, ICC/IF, IHC
Description NB100-64931 recognizes the murine antigen ER-HR3. ER-HR3 is a cell surface antigen which is expressed by Langerhans cells in epithelium, a subset of mature macrophages and dendritic cells that are located predominantly in haematopoietic and lymphoid organs. Initial studies of ER-HR3 demonstrated expression on peripheral blood monocytes but recent studies suggest that expression is actually very low. During foetal development, ER-HR3 positive cells are localised to haemapoietic islands and are often associated with erythroid progenitor cells. The functions of the ER-HR3 antigen have not been established but reports suggest that the antigen may be involved in adult erythropoiesis and in the regulation of the immune response. Clone ER-HR3 does not inhibit T cell proliferation in antigen-specific T-cell proliferation studies. Clone ER-HR3 recognizes two proteins of approximately 69kD and 55kD under non-reducing conditions.
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Reviews & Ratings
DyLight 680 Excitation and Emission Spectra