ER-HR3 / DyLight 680 / ER-HR3
ER-HR3 / DyLight 680 / ER-HR3
Product Details
Supplier | Novus Biologicals, a Bio-Techne brand | |
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Catalog #: | NB100-64931FR (View supplier product page) | |
Size | 0.125 ml | |
Price | $464.00 | |
Antigen | ER-HR3 | |
Clone | ER-HR3 | |
Host | Rat | |
Isotype | IgG2c | |
Conjugate | DyLight 680 | |
Target Species | Mouse | |
Applications | FC, IHC-Fr, ICC/IF, IHC | |
Description | NB100-64931 recognizes the murine antigen ER-HR3. ER-HR3 is a cell surface antigen which is expressed by Langerhans cells in epithelium, a subset of mature macrophages and dendritic cells that are located predominantly in haematopoietic and lymphoid organs. Initial studies of ER-HR3 demonstrated expression on peripheral blood monocytes but recent studies suggest that expression is actually very low. During foetal development, ER-HR3 positive cells are localised to haemapoietic islands and are often associated with erythroid progenitor cells. The functions of the ER-HR3 antigen have not been established but reports suggest that the antigen may be involved in adult erythropoiesis and in the regulation of the immune response. Clone ER-HR3 does not inhibit T cell proliferation in antigen-specific T-cell proliferation studies. Clone ER-HR3 recognizes two proteins of approximately 69kD and 55kD under non-reducing conditions. |
Citations
Reviews & Ratings
DyLight 680 Excitation and Emission Spectra
$464.00
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