HAP1 / Biotin /
HAP1 / Biotin /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C689075-1 (View supplier product page) | |
| Size | 1 ml | |
| Price | ||
| Antigen | HAP1 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Biotin | |
| Target Species | Mouse | |
| Applications | WB | |
| Description | HAP1 Antibody (aa132-328, Biotin) |
About HAP1 and Biotin
| HAP1 | Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008] |
|---|
Citations
| Additional Sources |
|
|---|
