EP300 / Biotin /
EP300 / Biotin /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C686873-1 (View supplier product page) | |
| Size | 1 ml | |
| Price | ||
| Antigen | EP300 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Biotin | |
| Target Species | Human | |
| Applications | WB | |
| Description | EP300 / p300 Antibody (aa1351-1601, Biotin) |
About EP300 and Biotin
| EP300 | This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008] |
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Citations
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