Glutamate Dehydrogenase / Biotin /
Glutamate Dehydrogenase / Biotin /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C684311-200 (View supplier product page) | |
| Size | 200 μl | |
| Price | ||
| Antigen | Glutamate Dehydrogenase | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Biotin | |
| Target Species | Human, Mouse | |
| Applications | WB | |
| Description | GLUD1/Glutamate Dehydrogenase Antibody (Biotin) |
About Glutamate Dehydrogenase and Biotin
| Glutamate Dehydrogenase | This gene encodes glutamate dehydrogenase, which is a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid-induced insulin secretion. It is allosterically activated by ADP and inhibited by GTP and ATP. Activating mutations in this gene are a common cause of congenital hyperinsulinism. Alternative splicing of this gene results in multiple transcript variants. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Related pseudogenes have been identified on chromosomes 10, 18 and X. [provided by RefSeq, Jan 2016] |
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Citations
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