C/EBP beta / FITC /
C/EBP beta / FITC /
Product Details
Supplier | LifeSpan | |
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Catalog #: | LS-C498605-100 (View supplier product page) | |
Size | 100 μg | |
Price | ||
Antigen | C/EBP beta | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | FITC | |
Target Species | Human | |
Applications | ELISA | |
Description | C/EBP Beta / CEBPB Antibody (FITC) |
About C/EBP beta and FITC
C/EBP beta | This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain. The encoded protein functions as a homodimer but can also form heterodimers with CCAAT/enhancer-binding proteins alpha, delta, and gamma. Activity of this protein is important in the regulation of genes involved in immune and inflammatory responses, among other processes. The use of alternative in-frame AUG start codons results in multiple protein isoforms, each with distinct biological functions. [provided by RefSeq, Oct 2013] | |
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FITC | Fluorescein isothiocyanate (FITC) has an excitation peak at 495 nm and an emission peak at 519 nm. The name FITC is a misnomer in that the isothiocyanate is a reactive form of this dye. Once FITC is conjugated to an antibody, it is simply Fluorescein conjugated. FITC is one of the most widely used dyes for fluorescent applications, therefore most instruments come standard with a 488 nm laser and FITC filter set up. FITC is commonly conjugated to secondary antibodies and used in applications such as flow cytometry, immunocytochemistry, and immunohistochemistry. FITC is relatively dim, sensitive to photobleaching and it is susceptible to changes is pH. There are better performing alternatives to FITC, like Vio®Bright 515, Alexa Fluor™ 488, iFluor® 488, CF®488A and DY-488. FITC is a long-time generic dye with no sole manufacturer or trademark. |