PD-1 / DyLight 350 / J116

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-43107UV (View supplier product page)
Size 0.1 ml
Price $529.00
Antigen PD-1
Clone J116
Host Mouse
Isotype IgG1 κ
Conjugate DyLight 350
Target Species Human
Applications WB, FC, IHC-Fr, IHC
About PD-1 and DyLight 350
PD-1 Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity. [provided by RefSeq, Aug 2020]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra