Caspase 4 / Biotin /
Caspase 4 / Biotin /
Product Details
Supplier | LifeSpan | |
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Catalog #: | LS-C299854-100 (View supplier product page) | |
Size | 100 μl | |
Price | ||
Antigen | Caspase 4 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | Biotin | |
Target Species | Bovine | |
Applications | WB | |
Description | CASP4 / Caspase 4 Antibody (aa290-377, Biotin) |
About Caspase 4 and Biotin
Caspase 4 | This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008] |
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