COL17A1 / Biotin /
COL17A1 / Biotin /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C298142-200 (View supplier product page) | |
| Size | 200 μl | |
| Price | ||
| Antigen | COL17A1 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Biotin | |
| Target Species | Human, Rat | |
| Applications | ||
| Description | COL17A1 / Collagen XVII Antibody (aa184-375, Biotin) |
About COL17A1 and Biotin
| COL17A1 | This gene encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. [provided by RefSeq, Jul 2008] |
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Citations
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