CD38 / Biotin / HIT2
CD38 / Biotin / HIT2
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C105947-25 (View supplier product page) | |
| Size | 25 μg | |
| Price | ||
| Antigen | CD38 | |
| Clone | HIT2 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | Biotin | |
| Target Species | Human | |
| Applications | FC | |
| Description | CD38 Antibody (clone HIT2, Biotin) |
About CD38 and Biotin
| CD38 | The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
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Citations
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