CD111 / Unconjugated / R1.302
CD111 / Unconjugated / R1.302
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C664201 (View supplier product page) | |
| Size | 100 μg | |
| Price | $302.00 | |
| Antigen | CD111 | |
| Clone | R1.302 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | FC, ICC, IHC, IP, WB | |
| Description | Nectin-1 / PVRL1 Antibody (clone R1.302) |
About CD111 and Purified
| CD111 | This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini. [provided by RefSeq, Oct 2009] |
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Citations
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