FluoroFinder

	Supplier	LifeSpan
	Catalog #:	LS-C662879 (View supplier product page)
	Size	100 Tests
	Price
	Antigen	4-1 BB Receptor
	Clone	4B4-1
	Host	Mouse
	Isotype	IgG1
	Conjugate	PE
	Target Species	Human, Non-Human Primate
	Applications	ELISA, FC, Functional, IP
	Description	TNFRSF9 / 4-1BB / CD137 Antibody (clone 4B4-1, PE)

	4-1 BB Receptor	The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]
	PE	Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.

	Additional Sources

4-1 BB Receptor / PE / 4B4-1