MDC1 / DyLight 350 / P2B11

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-12890UV (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen MDC1
Clone P2B11
Host Mouse
Isotype IgG1
Conjugate DyLight 350
Target Species Bovine, Human, Mouse, Non-Human Primate
Applications WB, ICC/IF
Description Detects approx 184kDa. This antibody recognizes MDC1 at and around the N-terminus.
About MDC1 and DyLight 350
MDC1 The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. [provided by RefSeq, Jul 2008]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra