CD44 / DyLight 405 / VFF-8

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-65533V (View supplier product page)
Size 0.1 ml
Price $559.00
Antigen CD44
Clone VFF-8
Host Mouse
Isotype IgG1
Conjugate DyLight 405
Target Species Human
Applications WB, FC, IHC-Fr, IHC-P, IHC
Description Specifically recognizes an epitope encoded by exon v5 on the variant portion of human CD44.
About CD44 and DyLight 405
CD44 The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
DyLight 405 DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 405 Excitation and Emission Spectra