Desmoglein-3 / DyLight 350 / 5G11

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-1643UV (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen Desmoglein-3
Clone 5G11
Host Mouse
Isotype IgG1
Conjugate DyLight 350
Target Species Human
Applications WB, IHC-P, ICC/IF, FC, IHC
Description This antibody reacts with Desmoglein 3. Does not cross-react with Desmoglein 1 or Desmoglein 2.
About Desmoglein-3 and DyLight 350
Desmoglein-3 This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris. [provided by RefSeq, Jan 2016]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra