CD8b / DyLight 350 / EP42

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-28300UV (View supplier product page)
Size 0.25 ml
Price $549.00
Antigen CD8b
Clone EP42
Host Mouse
Isotype IgG2a κ
Conjugate DyLight 350
Target Species Chicken
Applications FC, IHC-Fr, IHC
Description beta chain (Mr 34 kDa) of chicken CD8
About CD8b and DyLight 350
CD8b The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq, May 2010]
DyLight 350 DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 350 Excitation and Emission Spectra