VEGF-C / FITC /
VEGF-C / FITC /
Product Details
Supplier | LifeSpan | |
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Catalog #: | LS-C530567 (View supplier product page) | |
Size | 200 μl | |
Price | ||
Antigen | VEGF-C | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | FITC | |
Target Species | Human | |
Applications | IHC, WB | |
Description | VEGFC Antibody (aa248-277, FITC) |
About VEGF-C and FITC
VEGF-C | The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. The encoded protein promotes angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. The proprotein is further cleaved into a fully processed form that can bind and activate VEGFR-2 and VEGFR-3 receptors. [provided by RefSeq, Apr 2014] | |
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FITC | Fluorescein isothiocyanate (FITC) has an excitation peak at 495 nm and an emission peak at 519 nm. The name FITC is a misnomer in that the isothiocyanate is a reactive form of this dye. Once FITC is conjugated to an antibody, it is simply Fluorescein conjugated. FITC is one of the most widely used dyes for fluorescent applications, therefore most instruments come standard with a 488 nm laser and FITC filter set up. FITC is commonly conjugated to secondary antibodies and used in applications such as flow cytometry, immunocytochemistry, and immunohistochemistry. FITC is relatively dim, sensitive to photobleaching and it is susceptible to changes is pH. There are better performing alternatives to FITC, like Vio®Bright 515, Alexa Fluor™ 488, iFluor® 488, CF®488A and DY-488. FITC is a long-time generic dye with no sole manufacturer or trademark. |