BAI1 / DyLight 405 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB110-81586V (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen BAI1
Clone
Host Rabbit
Isotype IgG
Conjugate DyLight 405
Target Species Human, Mouse
Applications IHC-P, ICC/IF, WB, IHC
Description Rabbit BAI1 antibody [DyLight 405] detects Human, Mouse
About BAI1 and DyLight 405
BAI1 Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas [provided by RefSeq, Jul 2008]
DyLight 405 DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 405 Excitation and Emission Spectra