CD357 / Biotin /
CD357 / Biotin /
Product Details
Supplier | LifeSpan | |
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Catalog #: | LS-C522201 (View supplier product page) | |
Size | 100 μl | |
Price | ||
Antigen | CD357 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | Biotin | |
Target Species | Human, Mouse | |
Applications | WB | |
Description | TNFRSF18 / GITR Antibody (Biotin) |
About CD357 and Biotin
CD357 | This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011] |
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