FluoroFinder

	Supplier	LifeSpan
	Catalog #:	LS-C519921 (View supplier product page)
	Size	100 μl
	Price
	Antigen	ZAP70
	Clone
	Host	Mouse
	Isotype	IgG1
	Conjugate	APC
	Target Species	Human, Mouse
	Applications	ICC, IP, WB
	Description	ZAP70 Antibody (APC)

	ZAP70	This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
	APC	Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.

	Additional Sources

ZAP70 / APC /