eIF4G1 / APC /
eIF4G1 / APC /
Product Details
Supplier | LifeSpan | |
---|---|---|
Catalog #: | LS-C516673 (View supplier product page) | |
Size | 100 μl | |
Price | ||
Antigen | eIF4G1 | |
Clone | ||
Host | Mouse | |
Isotype | IgG2a κ | |
Conjugate | APC | |
Target Species | Human | |
Applications | ELISA, WB | |
Description | EIF4G1 / EIF4G Antibody (APC) |
About eIF4G1 and APC
eIF4G1 | The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010] | |
---|---|---|
APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |