MCM7 / APC /
MCM7 / APC /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C515861 (View supplier product page) | |
| Size | 100 μl | |
| Price | ||
| Antigen | MCM7 | |
| Clone | ||
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | APC | |
| Target Species | Canine, Human, Mouse, Rat, Xenopus | |
| Applications | IF, IHC, IP, WB | |
| Description | MCM7 Antibody (APC) |
About MCM7 and APC
| MCM7 | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |
Citations
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