CHOP / DyLight 650 / 9C8

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB600-1335C (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen CHOP
Clone 9C8
Host Mouse
Isotype IgG2b κ
Conjugate DyLight 650
Target Species Human, Mouse, Primate, Rat
Applications WB, IHC-P, ICC/IF, IHC
Description Mouse GADD153/CHOP antibody [DyLight 650] detects Human, Mouse, Rat, Primate
About CHOP and DyLight 650
CHOP This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq, Aug 2010]
DyLight 650 DyLight™ 650 is a red-emitting fluorophore that excited by the 640 nm laser and collected using a 670/30 nm bandpass filter. DyLight™ 650 has an excitation peak at 652 nm and an emission peak at 672 nm, and is spectrally similar to Alexa Fluor™ 647 and Cy5. DyLight™ 650 is most commonly used in flow cytometery and fluorescence microscopy applications.
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DyLight 650 Excitation and Emission Spectra