FluoroFinder

	Supplier	BioLegend
	Catalog #:	353404 (View supplier product page)
	Size	100T
	Price	$323.00
	Antigen	CCR6
	Clone	G034E3
	Host	Mouse
	Isotype	IgG2b κ
	Conjugate	Alexa Fluor 647
	Target Species	Cynomolgus macaque, Human, Rhesus macaque
	Applications	FC
	Description	Alexa Fluor 647 anti-human CD196 (CCR6)

	CCR6	This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
	Alexa Fluor 647	Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.

		Human peripheral lymphocytes were stained with CD19 Alexa Fluor® 488 and CCR6 (clone G034E3) Alexa Fluor® 647 ( top) or mouse IgG2b, κ Alexa Fluor® 647 isotype control (bottom).