RNF216 / Biotin /
RNF216 / Biotin /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C464147 (View supplier product page) | |
| Size | 100 μl | |
| Price | ||
| Antigen | RNF216 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Biotin | |
| Target Species | Bovine, Chimpanzee, Gibbon, Human, Mouse, Orangutan, Porcine, Rat | |
| Applications | WB | |
| Description | RNF216 / TRIAD3 Antibody (aa101-150, Biotin) |
About RNF216 and Biotin
| RNF216 | This gene encodes a cytoplasmic protein which specifically colocalizes and interacts with the serine/threonine protein kinase, receptor-interacting protein (RIP). Zinc finger domains of the encoded protein are required for its interaction with RIP and for inhibition of TNF- and IL1-induced NF-kappa B activation pathways. The encoded protein may also function as an E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes and transfers it to substrates. Several alternatively spliced transcript variants have been described for this locus but the full-length natures of only some are known. [provided by RefSeq, Jul 2008] |
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Citations
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