CCR7 / APC / G043H7

Citations: (32)
Product Details
Supplier BioLegend
Catalog #: 353214 (View supplier product page)
Size 100T
Price $338.00
Antigen CCR7
Clone G043H7
Host Mouse
Isotype IgG2a κ
Conjugate APC
Target Species Human
Applications FC
Description APC anti-human CD197 (CCR7)
About CCR7 and APC
CCR7 The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
APC Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
Images
  CCR7 APC BioLegend antibody anti target:Human host:Mouse isotype:IgG2a κ clone:G043H7

Human peripheral blood lymphocytes were stained with CD3 FITC and CCR7 (clone G043H7) APC (top) or mouse IgG2a, κ APC isotype control (bottom).

  CCR7 APC BioLegend antibody anti target:Human host:Mouse isotype:IgG2a κ clone:G043H7

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APC Excitation and Emission Spectra