CCR7 / APC-Cy7 / G043H7

Citations: (31)
Product Details
Supplier BioLegend
Catalog #: 353212 (View supplier product page)
Size 100T
Price $382.00
Antigen CCR7
Clone G043H7
Host Mouse
Isotype IgG2a κ
Conjugate APC-Cy7
Target Species Human
Applications FC
Description APC/Cyanine7 anti-human CD197 (CCR7)
About CCR7 and APC-Cy7
CCR7 The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]
APC-Cy7 APC-Cy7 (APC-Cyanine 7) has an excitation peak at 650 nm and an emission peak at 785 nm, and is spectrally similar to APC-CF®750 (Biotium), APC-H7 (BD Biosciences), APC-eFluor™ 780 (Thermo Fisher Scientific), APC-Vio®770 (Miltenyi Biotec) and APC-Fire™ 750 (BioLegend). This dye is a member of the Cyanine® dye family, a trademark of GE heathcare.
Images
  CCR7 APC-Cy7 BioLegend antibody anti target:Human host:Mouse isotype:IgG2a κ clone:G043H7

Human peripheral blood lymphocytes were stained with CD3 FITC and CD197 (clone G043H7) APC/Cy7 (top) or mouse IgG2a, κ APC/Cy7 isotype control (bottom).

  CCR7 APC-Cy7 BioLegend antibody anti target:Human host:Mouse isotype:IgG2a κ clone:G043H7

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APC-Cy7 Excitation and Emission Spectra