CCR7 / APC-Cy7 / G043H7
CCR7 / APC-Cy7 / G043H7
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(31)
Product Details
Supplier | BioLegend | |
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Catalog #: | 353212 (View supplier product page) | |
Size | 100T | |
Price | $382.00 | |
Antigen | CCR7 | |
Clone | G043H7 | |
Host | Mouse | |
Isotype | IgG2a κ | |
Conjugate | APC-Cy7 | |
Target Species | Human | |
Applications | FC | |
Description | APC/Cyanine7 anti-human CD197 (CCR7) |
About CCR7 and APC-Cy7
CCR7 | The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014] | |
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APC-Cy7 | APC-Cy7 (APC-Cyanine 7) has an excitation peak at 650 nm and an emission peak at 785 nm, and is spectrally similar to APC-CF®750 (Biotium), APC-H7 (BD Biosciences), APC-eFluor™ 780 (Thermo Fisher Scientific), APC-Vio®770 (Miltenyi Biotec) and APC-Fire™ 750 (BioLegend). This dye is a member of the Cyanine® dye family, a trademark of GE heathcare. |
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APC-Cy7 Excitation and Emission Spectra
$382.00
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