ASCC1 / HRP /
ASCC1 / HRP /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C462417 (View supplier product page) | |
| Size | 100 μl | |
| Price | ||
| Antigen | ASCC1 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | HRP | |
| Target Species | Bovine, Canine, Equine, Gibbon, Goat, Human, Mouse, Rabbit, Rat | |
| Applications | WB | |
| Description | ASCC1 Antibody (C-Terminus, HRP) |
About ASCC1 and HRP
| ASCC1 | This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
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Citations
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