SHP2 / HRP /
SHP2 / HRP /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C461867 (View supplier product page) | |
| Size | 100 μl | |
| Price | ||
| Antigen | SHP2 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | HRP | |
| Target Species | Bovine, Canine, Equine, Guinea Pig, Human, Mouse, Porcine, Rabbit, Rat, Zebrafish | |
| Applications | WB | |
| Description | PTPN11 / SHP-2 / NS1 Antibody (N-Terminus, HRP) |
About SHP2 and HRP
| SHP2 | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016] |
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Citations
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