FluoroFinder

	Supplier	BioLegend
	Catalog #:	346006 (View supplier product page)
	Size	100T
	Price	$298.00
	Antigen	CD169
	Clone	7-239
	Host	Mouse
	Isotype	IgG1 κ
	Conjugate	Alexa Fluor 647
	Target Species	Human
	Applications	FC
	Description	Alexa Fluor 647 anti-human CD169 (Sialoadhesin, Siglec-1)

	CD169	This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008]
	Alexa Fluor 647	Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.

		Human peripheral blood monocytes were stimulated with TNF-α plus IFN-γ for 3 days, then stained with CD14 FITC and CD169 (clone 7-239) Alexa Fluor® 647 (top) or mouse IgG1, κ Alexa Fluor® 647 isotype control (bottom).