IL-1 RL2 / FITC /
IL-1 RL2 / FITC /
Product Details
Supplier | LifeSpan | |
---|---|---|
Catalog #: | LS-C448844 (View supplier product page) | |
Size | 100 μl | |
Price | ||
Antigen | IL-1 RL2 | |
Clone | ||
Host | Rabbit | |
Isotype | IgG | |
Conjugate | FITC | |
Target Species | Canine, Equine, Human | |
Applications | WB | |
Description | IL1RL2 Antibody (aa107-156, FITC) |
About IL-1 RL2 and FITC
IL-1 RL2 | The protein encoded by this gene is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. This gene and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. [provided by RefSeq, Jul 2008] | |
---|---|---|
FITC | Fluorescein isothiocyanate (FITC) has an excitation peak at 495 nm and an emission peak at 519 nm. The name FITC is a misnomer in that the isothiocyanate is a reactive form of this dye. Once FITC is conjugated to an antibody, it is simply Fluorescein conjugated. FITC is one of the most widely used dyes for fluorescent applications, therefore most instruments come standard with a 488 nm laser and FITC filter set up. FITC is commonly conjugated to secondary antibodies and used in applications such as flow cytometry, immunocytochemistry, and immunohistochemistry. FITC is relatively dim, sensitive to photobleaching and it is susceptible to changes is pH. There are better performing alternatives to FITC, like Vio®Bright 515, Alexa Fluor™ 488, iFluor® 488, CF®488A and DY-488. FITC is a long-time generic dye with no sole manufacturer or trademark. |