CD163 / Alexa Fluor 647 / RM3/1
CD163 / Alexa Fluor 647 / RM3/1
Citations:
(4)
Product Details
| Supplier | BioLegend | |
|---|---|---|
| Catalog #: | 326508 (View supplier product page) | |
| Size | 100T | |
| Price | $265.00 | |
| Antigen | CD163 | |
| Clone | RM3/1 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | Alexa Fluor 647 | |
| Target Species | Human | |
| Applications | FC | |
| Description | Alexa Fluor 647 anti-human CD163 |
About CD163 and Alexa Fluor 647
| CD163 | The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011] | |
|---|---|---|
| Alexa Fluor 647 | Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye. |
Images
|
IL-10-stimulated (overnight) human peripheral blood monocytes were stained with CD163 (clone RM3/1) Alexa Fluor® 647 (filled histogram) or mouse IgG1, κ Alexa Fluor® 647 isotype control (open histogram). |
Citations
| PMID 19951991 | ||
|---|---|---|
| PMID 23224400 | ||
| Additional Sources |
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Reviews & Ratings
Alexa Fluor 647 Excitation and Emission Spectra
$265.00
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