CD326 / FITC / 9C4
CD326 / FITC / 9C4
Citations:
(25)
Product Details
Supplier | BioLegend | |
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Catalog #: | 324203 (View supplier product page) | |
Size | 25T | |
Price | $106.00 | |
Antigen | CD326 | |
Clone | 9C4 | |
Host | Mouse | |
Isotype | IgG2b κ | |
Conjugate | FITC | |
Target Species | Human | |
Applications | FC | |
Description | FITC anti-human CD326 (Ep-CAM) |
About CD326 and FITC
CD326 | This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008] | |
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FITC | Fluorescein isothiocyanate (FITC) has an excitation peak at 495 nm and an emission peak at 519 nm. The name FITC is a misnomer in that the isothiocyanate is a reactive form of this dye. Once FITC is conjugated to an antibody, it is simply Fluorescein conjugated. FITC is one of the most widely used dyes for fluorescent applications, therefore most instruments come standard with a 488 nm laser and FITC filter set up. FITC is commonly conjugated to secondary antibodies and used in applications such as flow cytometry, immunocytochemistry, and immunohistochemistry. FITC is relatively dim, sensitive to photobleaching and it is susceptible to changes is pH. There are better performing alternatives to FITC, like Vio®Bright 515, Alexa Fluor™ 488, iFluor® 488, CF®488A and DY-488. FITC is a long-time generic dye with no sole manufacturer or trademark. |
Images
Citations
PMID 20615947 | ||
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PMID 24046446 | ||
PMID 24124593 | ||
PMID 24694753 | ||
Additional Sources |
Reviews & Ratings
FITC Excitation and Emission Spectra
$106.00
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