FluoroFinder

	Supplier	LifeSpan
	Catalog #:	LS-C446460 (View supplier product page)
	Size	100 μl
	Price
	Antigen	Cyclophilin B
	Clone
	Host	Rabbit
	Isotype	IgG
	Conjugate	FITC
	Target Species	Canine, Chimpanzee, Equine, Gibbon, Guinea Pig, Hamster, Human, Monkey, Mouse, Zebrafish
	Applications	IHC, IHC-P, WB
	Description	PPIB / Cyclophilin B Antibody (C-Terminus, FITC)

	Cyclophilin B	The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq, Oct 2009]
	FITC	Fluorescein isothiocyanate (FITC) has an excitation peak at 495 nm and an emission peak at 519 nm. The name FITC is a misnomer in that the isothiocyanate is a reactive form of this dye. Once FITC is conjugated to an antibody, it is simply Fluorescein conjugated. FITC is one of the most widely used dyes for fluorescent applications, therefore most instruments come standard with a 488 nm laser and FITC filter set up. FITC is commonly conjugated to secondary antibodies and used in applications such as flow cytometry, immunocytochemistry, and immunohistochemistry. FITC is relatively dim, sensitive to photobleaching and it is susceptible to changes is pH. There are better performing alternatives to FITC, like Vio®Bright 515, Alexa Fluor™ 488, iFluor® 488, CF®488A and DY-488. FITC is a long-time generic dye with no sole manufacturer or trademark.

	Additional Sources

Cyclophilin B / FITC /