AGR2 / HRP /
AGR2 / HRP /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C443497 (View supplier product page) | |
| Size | 100 μl | |
| Price | ||
| Antigen | AGR2 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | HRP | |
| Target Species | Bovine, Canine, Chimpanzee, Equine, Gibbon, Guinea Pig, Human, Monkey, Mouse, Orangutan, Rabbit, Rat, Xenopus, Zebrafish | |
| Applications | IHC, IHC-P, WB | |
| Description | AGR2 Antibody (aa101-150, HRP) |
About AGR2 and HRP
| AGR2 | This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. [provided by RefSeq, Mar 2017] |
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Citations
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