CD49f / Alexa Fluor 647 / GoH3
CD49f / Alexa Fluor 647 / GoH3
Citations:
(29)
Product Details
| Supplier | BioLegend | |
|---|---|---|
| Catalog #: | 313610 (View supplier product page) | |
| Size | 100T | |
| Price | $268.00 | |
| Antigen | CD49f | |
| Clone | GoH3 | |
| Host | Rat | |
| Isotype | IgG2a κ | |
| Conjugate | Alexa Fluor 647 | |
| Target Species | Cynomolgus macaque, Human, Mouse, Rhesus macaque | |
| Applications | FC | |
| Description | Alexa Fluor 647 anti-human/mouse CD49f |
About CD49f and Alexa Fluor 647
| CD49f | The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015] | |
|---|---|---|
| Alexa Fluor 647 | Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye. |
Images
|
Human peripheral blood lymphocytes stained with GoH3 Alexa Fluor® 647 |
Citations
Reviews & Ratings
Alexa Fluor 647 Excitation and Emission Spectra
$268.00
Supplier Page
Supplier Page
