IKZF3 / Biotin /
IKZF3 / Biotin /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C439058 (View supplier product page) | |
| Size | 100 μl | |
| Price | ||
| Antigen | IKZF3 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Biotin | |
| Target Species | Bovine, Chimpanzee, Equine, Gibbon, Guinea Pig, Human, Porcine, Rabbit | |
| Applications | WB | |
| Description | IKZF3 / AIOLOS Antibody (aa181-230, Biotin) |
About IKZF3 and Biotin
| IKZF3 | This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012] |
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Citations
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