CD38 / PerCP-Cy5.5 / HIT2
CD38 / PerCP-Cy5.5 / HIT2
Citations:
(31)
Product Details
| Supplier | BioLegend | |
|---|---|---|
| Catalog #: | 303522 (View supplier product page) | |
| Size | 100T | |
| Price | $382.00 | |
| Antigen | CD38 | |
| Clone | HIT2 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | PerCP-Cy5.5 | |
| Target Species | Human | |
| Applications | FC | |
| Description | PerCP/Cyanine5.5 anti-human CD38 |
About CD38 and PerCP-Cy5.5
| CD38 | The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] | |
|---|---|---|
| PerCP-Cy5.5 | PerCP-Cyanine® 5.5 (PerCP-Cy5.5) is a red-emitting tandem fluorophore that was originally designed to make the PerCP fluorophore more stable and increase signal intensity. The donor molecule, PerCP can be excited by the 488-nm blue laser and and transfers energy to the acceptor molecule, Cy5.5, which emitts light that can be captured with a 695/40 nm bandpass filter. PerCP-Cy5.5 has an excitation peak at 482 nm and an emission peak at 695 nm. There are superior alternatives to PerCP and PerCP-Cy5.5 including RealBlue 705 (BD Biosciences), NovaFluor Blue 690 or PerCP-eFluor™ 710. |
Images
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Human peripheral blood lymphocytes were stained with CD38 (clone HIT2) PerCP/Cyanine5.5 (filled histogram) or mouse IgG1, κ PerCP/Cyanine5.5 isotype control (open histogram). |
Citations
| PMID 18182458 | ||
|---|---|---|
| Additional Sources |
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Reviews & Ratings
PerCP-Cy5.5 Excitation and Emission Spectra
$382.00
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