CD38 / Alexa Fluor 647 / HIT2
CD38 / Alexa Fluor 647 / HIT2
Citations:
(11)
Product Details
Supplier | BioLegend | |
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Catalog #: | 303514 (View supplier product page) | |
Size | 100T | |
Price | $265.00 | |
Antigen | CD38 | |
Clone | HIT2 | |
Host | Mouse | |
Isotype | IgG1 κ | |
Conjugate | Alexa Fluor 647 | |
Target Species | Human | |
Applications | FC | |
Description | Alexa Fluor 647 anti-human CD38 |
About CD38 and Alexa Fluor 647
CD38 | The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] | |
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Alexa Fluor 647 | Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye. |
Images
Citations
PMID 18182458 | ||
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Additional Sources |
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Reviews & Ratings
Alexa Fluor 647 Excitation and Emission Spectra
$265.00
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