CD38 / Alexa Fluor 647 / HIT2

Citations: (11)
Product Details
Supplier BioLegend
Catalog #: 303514 (View supplier product page)
Size 100T
Price $265.00
Antigen CD38
Clone HIT2
Host Mouse
Isotype IgG1 κ
Conjugate Alexa Fluor 647
Target Species Human
Applications FC
Description Alexa Fluor 647 anti-human CD38
About CD38 and Alexa Fluor 647
CD38 The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
Images
  CD38 Alexa Fluor 647 BioLegend antibody anti target:Human host:Mouse isotype:IgG1 κ clone:HIT2

Human peripheral blood lymphocytes stained with HIT2 Alexa Fluor® 647

Citations
PMID 18182458
Additional
Sources
Reviews & Ratings
Alexa Fluor 647 Excitation and Emission Spectra