CD14 / PerCP-Cy5.5 / M5E2
CD14 / PerCP-Cy5.5 / M5E2
Product Details
| Supplier | BioLegend | |
|---|---|---|
| Catalog #: | 301823 (View supplier product page) | |
| Size | 25T | |
| Price | $176.00 | |
| Antigen | CD14 | |
| Clone | M5E2 | |
| Host | Mouse | |
| Isotype | IgG2a κ | |
| Conjugate | PerCP-Cy5.5 | |
| Target Species | Cynomolgus macaque, Human, Rhesus macaque | |
| Applications | FC | |
| Description | PerCP/Cyanine5.5 anti-human CD14 |
About CD14 and PerCP-Cy5.5
| CD14 | The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2020] | |
|---|---|---|
| PerCP-Cy5.5 | PerCP-Cyanine® 5.5 (PerCP-Cy5.5) is a red-emitting tandem fluorophore that was originally designed to make the PerCP fluorophore more stable and increase signal intensity. The donor molecule, PerCP can be excited by the 488-nm blue laser and and transfers energy to the acceptor molecule, Cy5.5, which emitts light that can be captured with a 695/40 nm bandpass filter. PerCP-Cy5.5 has an excitation peak at 482 nm and an emission peak at 695 nm. There are superior alternatives to PerCP and PerCP-Cy5.5 including RealBlue 705 (BD Biosciences), NovaFluor Blue 690 or PerCP-eFluor™ 710. |
Images
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Human peripheral blood monocytes were stained with CD14 (clone M5E2) PerCP/Cyanine5.5 (filled histogram), or mouse IgG2a, κ PerCP/Cyanine5.5 isotype control (open histogram). |
Citations
| PMID 17641010 | ||
|---|---|---|
| PMID 20844193 | ||
| PMID 22942426 | ||
| Additional Sources |
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Reviews & Ratings
PerCP-Cy5.5 Excitation and Emission Spectra
$176.00
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