CD14 / Alexa Fluor 647 / M5E2

Citations: (6)
Product Details
Supplier BioLegend
Catalog #: 301818 (View supplier product page)
Size 25T
Price $112.00
Antigen CD14
Clone M5E2
Host Mouse
Isotype IgG2a κ
Conjugate Alexa Fluor 647
Target Species Cynomolgus macaque, Human, Rhesus macaque
Applications FC
Description Alexa Fluor 647 anti-human CD14
About CD14 and Alexa Fluor 647
CD14 The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2020]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
Images
  CD14 Alexa Fluor 647 BioLegend antibody anti target:Cynomolgus macaque, Human, Rhesus macaque host:Mouse isotype:IgG2a κ clone:M5E2

Human peripheral blood monocytes stained with M5E2 Alexa Fluor® 647

Citations
Reviews & Ratings
Alexa Fluor 647 Excitation and Emission Spectra