CD14 / PE-Cy7 / M5E2

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Product Details
Supplier BioLegend
Catalog #: 301813 (View supplier product page)
Size 25T
Price $143.00
Antigen CD14
Clone M5E2
Host Mouse
Isotype IgG2a κ
Conjugate PE-Cy7
Target Species Cynomolgus macaque, Human, Rhesus macaque
Applications FC
Description PE/Cyanine7 anti-human CD14
About CD14 and PE-Cy7
CD14 The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2020]
PE-Cy7 PE-Cyanine®7 (PE-Cy7, RPE-Cy7) is a far red-emitting tandem fluorophore that combines phycoerythrin (PE) and Cy7. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Cy7, which emits light that can be captured with a 780/60 nm bandpass filter. PE-CY7 has an excitation peak at 565 nm and an emission peak at 778 nm, and is a suitable alternative to PE-Vio®770 (Miltenyi) and cFluor BYG781 (Cytek).
Images
  CD14 PE-Cy7 BioLegend antibody anti target:Cynomolgus macaque, Human, Rhesus macaque host:Mouse isotype:IgG2a κ clone:M5E2

Human peripheral blood monocytes stained with M5E2 PE/Cy7

Citations
PE-Cy7 Excitation and Emission Spectra