HIF-1 beta / Biotin /
HIF-1 beta / Biotin /
Product Details
| Supplier | LifeSpan | |
|---|---|---|
| Catalog #: | LS-C426142 (View supplier product page) | |
| Size | 100 μl | |
| Price | ||
| Antigen | HIF-1 beta | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Biotin | |
| Target Species | Bat, Bovine, Canine, Equine, Gibbon, Guinea Pig, Human, Monkey, Mouse, Porcine, Rabbit, Rat | |
| Applications | WB | |
| Description | ARNT / HIF-1-Beta Antibody (aa51-100, Biotin) |
About HIF-1 beta and Biotin
| HIF-1 beta | This gene encodes a protein containing a basic helix-loop-helix domain and two characteristic PAS domains along with a PAC domain. The encoded protein binds to ligand-bound aryl hydrocarbon receptor and aids in the movement of this complex to the nucleus, where it promotes the expression of genes involved in xenobiotic metabolism. This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1. Chromosomal translocation of this locus with the ETV6 (ets variant 6) gene on chromosome 12 have been described in leukemias. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2013] |
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Citations
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