CD133 / APC / 315-2C11

Citations: (13)
Product Details
Supplier BioLegend
Catalog #: 141207 (View supplier product page)
Size 25 μg
Price $142.00
Antigen CD133
Clone 315-2C11
Host Rat
Isotype IgG2a λ
Conjugate APC
Target Species Mouse
Applications FC
Description APC anti-mouse CD133
About CD133 and APC
CD133 This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
APC Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
Images
  CD133 APC BioLegend antibody anti target:Mouse host:Rat isotype:IgG2a λ clone:315-2C11

Mouse CD133 transfected cells were stained with CD133 (clone 315-2C11) APC (filled histogram) or rat IgG2a, κ APC isotype control (open histogram).

  CD133 APC BioLegend antibody anti target:Mouse host:Rat isotype:IgG2a λ clone:315-2C11

C57BL/6 mouse bone marrow cells were stained with FITC-conjugated Ly-6G, CD3 and B220, CD117 PE, and CD133 (clone 315-2C11) APC (middle) or rat IgG2a, κ APC (bottom) isotype control. Data was gated on Ly-6G/CD3/B220 negative cell population.

  CD133 APC BioLegend antibody anti target:Mouse host:Rat isotype:IgG2a λ clone:315-2C11

Citations
PMID 22596053
Additional
Sources
Reviews & Ratings
APC Excitation and Emission Spectra