NKp46 / Brilliant Violet 421 / 29A1.4
NKp46 / Brilliant Violet 421 / 29A1.4
Product Details
| Supplier | BioLegend | |
|---|---|---|
| Catalog #: | 137611 (View supplier product page) | |
| Size | 125UL | |
| Price | $204.00 | |
| Antigen | NKp46 | |
| Clone | 29A1.4 | |
| Host | Rat | |
| Isotype | IgG2a κ | |
| Conjugate | Brilliant Violet 421 | |
| Target Species | Mouse | |
| Applications | FC | |
| Description | Brilliant Violet 421 anti-mouse CD335 (NKp46) |
About NKp46 and Brilliant Violet 421
| NKp46 | Predicted to be involved in cellular defense response; regulation of natural killer cell mediated cytotoxicity; and signal transduction. Predicted to act upstream of or within defense response to virus and detection of virus. Predicted to be located in cell surface. Predicted to be part of SWI/SNF complex. Predicted to be active in plasma membrane. Biomarker of acquired immunodeficiency syndrome; anogenital venereal wart; hepatitis C; and lymphoproliferative syndrome. [provided by Alliance of Genome Resources, Apr 2022] | |
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| Brilliant Violet 421 | Brilliant™ Violet 421 (BV421) is a Violet-emitting non-tandem polymer fluorophore that can be excited by the 405 nm Violet laser and collected using a 450/50 bandpass filter. BV421 has an excitation peak at 405 nm and an emission peak at 421 nm, and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. Other similar fluorophores include SuperNova V428 (Beckman Coulter), StarBright Violet 440 (Bio-Rad) and SuperBright 436 (Thermo Fisher). BV421 is very bright and is most commonly used for flow cytometry. BV421 is very photo- and fixative stable. This dye is part of the Brilliant™ Violet dye line of fluorescent polymers. Brilliant™ Violet 421 polymer is employed as the donor molecule in a series of tandem dyes with acceptor molecules emitting at various points across the visible light spectrum. The Brilliant™ Violet dyes are a superior alternative to QDot nanocrystals and similar to SuperNova dyes from Beckman Coulter and StarBright dyes from Bio-Rad. |
Images
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C57BL/6 splenocytes stained with NK1.1 APC and NKp46 (clone 29A1.4) Brilliant Violet 421™ (top) or rat IgG2a Brilliant Violet 421™ isotype control (bottom). |
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Citations
| PMID 21300822 | ||
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| Additional Sources |
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Reviews & Ratings
Brilliant Violet 421 Excitation and Emission Spectra
$204.00
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